＆The Center of Medical Innovation and Translational ResearchImmunopharmaceutical Development UnitRegenerative Medicine UnitImmunity andRegeneration Integration UnitNovel Integrated Area UnitPage Unit ProjectPrincipal InvestigatorProfessor NAKATA KenDepartment of Medicine for Sports and Performing ArtsProfessor NAKATA KenDepartment of Medicine for Sports and Performing ArtsSpecially Appointed Professor NARAZAKI MasashiDepartment of Advanced Clinical and Translational ImmunologyEndowed Chair Associate Professor OKA KunihiroDepartment of Orthopedic Biomaterial ScienceProfessor KUTSUNA SatoshiDepartment of Infection Control and PreventionSpecially Appointed Professor MATSUZAKI TakashiDepartment of DDS Pharmaceutical DevelopmentSpecially Appointed Professor HIRATA MasayukiDepartment of Neurological Diagnosis and RestorationSpecially Appointed Professor HIDA EisukeDepartment of Biostatistics and Data ScienceSpecially Appointed Professor TANIYAMA YoshiakiDepartment of Advanced Molecular TherapySpecially Appointed Professor OHKURA Naganari Department of Frontier Research in Tumor ImmunologySpecially Appointed Associate Professor SAITO TakuroDepartment of Clinical Research in Tumor ImmunologySpecially Appointed Associate Professor KIKUCHI YasushiDepartment of Stem Cell Gene Therapy ScienceEndowed Chair Associate Professor SAGA Kotaro Department of Stem Cell Therapy ScienceProfessor KISHIMA HaruhikoDepartment of NeurosurgerySpecially Appointed Professor ISHII HideshiDepartment of Medical Data ScienceEndowed Chair Associate Professor SAKIMOTO SusumuDepartment of Stem Cells and Applied MedicineProfessor NISHIDA KohjiDepartment of OphthalmologyProfessor NISHIDA KohjiDepartment of OphthalmologyProfessor NISHIDA KohjiDepartment of OphthalmologyEndowed Chair Professor MORISHITA RyuichiDepartment of Clinical Gene TherapyStem Cell Endowed Chair Assistant Professor CHANG Chin-YangStem Cell Regenerative TherapyDepartment of GeneAssociate Professor YOSHITO TakedaDepartment of Respiratory Medicine and Clinical ImmunologyProfessor HOSEN NaokiDepartment of Hematoiogy and OncologyProfessor YAMASHITA ToshihideDepartment of Molecular NeuroscienceEndowed Chair Professor MORISHITA RyuichiDepartment of Clinical Gene TherapyEndowed Chair Professor NAKAGAMI HironoriDepartment of Health Development and MedicineProfessor FUJIMOTO ManabuDepartment of DermatologyProfessor FUJIMOTO ManabuDepartment of DermatologyResponsible DepartmentsDepartment of Sports Medical ScienceDepartment of Sports Medical BiomechanicsDepartment of Advanced Clinical and Translational ImmunologyDepartment of Orthopedic Biomaterial ScienceDepartment of Post-infectious diseases TherapeuticsDepartment of DDS Pharmaceutical DevelopmentDepartment of Neurological Diagnosis and RestorationDepartment of Biostatistics and Data ScienceDepartment of Advanced Molecular TherapyDepartment of Frontier Research in Tumor ImmunologyDepartment of Clinical Research in Tumor ImmunologyDepartment of Stem Cell Gene Therapy ScienceDepartment of Stem Cell Therapy ScienceDepartment of NeurosurgeryDepartment of Medical Data ScienceDepartment of Stem Cells and Applied MedicineDepartment of Vision Informatics Department of Advanced Device Regenerative MedicineDepartment of Ocular Immunology and Regenerative MedicineDepartment of Clinical Gene TherapyDepartment of Gene＆Regenerative Therapy Department of Immunology and Molecular MedicineDepartment of Device Application for Molecular TherapeuticsDepartment of Neuro-Medical ScienceDepartment of Clinical Gene TherapyDepartment of Health Development and MedicineDepartment of Cutaneous Immunology and MicrobiologyDepartment of Medicine for Cutaneous Immunological Diseases Research and Development Department INDEX1834 ●26 ●23 ●27 ●34 ●24 ●35 ●35 ●22 ● Analysis of the functions of pathological or physiological periostinThe development of immunotherapy targeting immune suppressive molecules and cells22 ●23 ● Clinical research for regulatory factors in tumor immunology30 ●31 ●33 ●31 ●25 ●33 ●26 ●29 ●21 ● Next-generation digital biomarker for early diagnosis of dementiaDevelopment of next-generation designer cell with improved adipose-derived stem cells (ADSCs)21 ●30 ●32 ●28 ●19 ●20 ● Therapeutic Vaccines as Next Generation Biologics29 ●20 ●Research and development of social implementation on health maintenance by integration of musculoskeletal regenerative medicine and sports/health epidemiologyDevelopment of medical devices, biomechanical evaluation methods of activity, and development of new regenerative therapy for sports injuries, disorders and diseasesDevelopment of innovative therapies for intractable immune disease and cancer by targeting neuro, immune and metabolic regulatory factorsDevelopment of computer-aided diagnosis programs and patient-matched instrumentsResearch Evaluation of Safety and Impact in Long COVID Intervention with Ensitrelvir for National Cohort Efficacy (RESILIENCE study)Development of cGMP manufacturing process for novel lipid-based nano-medicine by taking advantage of the in-line manufacturing platform technologyResearch and development of neural informatics, modulation and restorationBuilding new clinical evidence by integrating clinical trial data and real world data (RWD)Development of stem cell-based gene therapy adapted for the regeneration-inducing medicineDevelopment of novel medicine for inducing scarless and functional tissue regeneration by mobilizing bone marrow mesenchymal stem cellsResearch and development of precision diagnostics by highly sensitive spectroscopy(Life and Medical Photonics Division, Institute for Open and Transdisciplinary Research Initiatives (OTRI))Establishing cancer profiling to develop innovative, personalized medicine and therapeuticsDevelopment of new technology for the manufacturing, standardization and application of stem cell-based productsExploration of Innovative Diagnostic and Therapeutic Approaches for Ocular Diseases:1. Development of advanced diagnostic imaging software2. Creation of diagnostic equipment and clinical indices that enhance decision-making in the diagnosis and treatment of both ophthalmic and systemic diseasesDevelopment of Innovative Medical Devices using Bionanotechnology and drug development for corneal regeneration medicineElucidation of the involvement of chronic inflammation during the pathogenic processes of various ophthalmic diseases and the creation of treatmentsDevelopment of immunomodulation technology and quality control technology in cell therapyResearch and development of advanced devices for next-generation medical careNew drugs for refractory neurological diseases through translational researchDevelopment of novel diagnostic and therapeutic approaches for treating aging-associated diseases1. Understanding the pathogenesis of inflammatory skin diseases associated with dysbiosis2. Analysis of the impact of maintaining skin homeostasis on overall health spanElucidation of pathological mechanisms in cutaneous immune-mediated disorders and validation of therapeutic targetsThe Center of Medical Innovation and Translational Research9F8F7F6F
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