4The Center of Medical Innovation and Translational ResearchDirector The University of Osaka HospitalNONOMURA NorioDirectorCenter of Medical Innovation and Translational ResearchFUJIMOTO ManabuIt has been 11 years since the Center of Medical Innovation and Translational Research (CoMIT) was established in the University of Osaka. CoMIT has been established as a research center to bridge basic medical research to clinical research and practical medicine.Osaka has prospered as a town of commerce and merchants since early times, cherishing everything that can “be of service to others.” This spirit, I believe, remains alive in medical research. At the Graduate School of Medicine, the University of Osaka, many researchers constantly devote themselves to research in the field of life science with an aspiration of conducting research that can be of service to others.There is an extremely long way to go for medical research to reach practical application in medical care. It can “be of service to others” only after going through the process of questioning “what the problem is in practical medical settings” and “what the reason is,” identifying the causative agents (proteins or genes), and achieving the development of diagnostic methods and medicines. Also, sometimes more sophisticated and safe medical care may only be achieved by the development of new medical devices through medical-industrial collaboration. In order for these underlying endeavors to be promoted smoothly, the Medical Center for Translational Research was established in 2002 in the University of Osaka Hospital and has since strived to bridge basic research to clinical practice. The center was later reorganized into the “Department of Medical Innovation” and has become an important institution that promotes not only translational research but also clinical research as a whole. In high recognition of such efforts, in 2015, the University of Osaka Hospital was certified as a Clinical Research Core Hospital based on the Medical Care Act of Japan.To further accelerate these efforts, industry-academia collaboration is essential. CoMIT was established to this end, and comprises the Research and Development Department, Common Fundamental Technology Department, and Research Support Department. The Research and Development Department plays a central role in CoMIT, where several industry-academia-government collaboration projects are currently underway by the Immunopharmaceutical Development, Regenerative Medicine, Immunity and Regeneration Integration, and Novel Integrated Area Units. Each unit has industry-academia collaborative research programs and industry-sponsored programs, and fascinating research is being promoted.The University of Osaka Hospital will provide full support for the seeds of basic research developed in CoMIT to be transformed through first-in-human trials into clinical implementation.Economy, Trade and Industry. CoMIT was then established in April 2014 as the culmination of leadership by 3 successive deans of the Graduate School of Medicine and hard work by numerous faculty members.CoMIT has a highly unique characteristics, where companies, universities, and researchers from different fields and areas gather “Under One Roof” of the same facility for development and practical application of integrative, cross-cutting, advanced medical technology in immunity, regeneration, and other areas. The number of projects promoted at CoMIT and participating companies is actually increasing every year, further enriching research to deliver multiple achievements. I hope CoMIT will continue to play an active role in bridging basic research to clinical research and social implementation as a center to create and deliver new innovations by integrating various areas of knowledge.In 2002, the Graduate School of Medicine of the University of Osaka established the Medical Center for Translational Research at the University of Osaka Hospital, and has become one of the first institutions in Japan to establish a system to develop basic technologies (from on and off campus) into advanced medical care. The next innovation expected was the preparation of the “soil” for promising basic technologies to flourish. As a key way to achieve this, the establishment of the Center of Medical Innovation and Translational Research (CoMIT) was proposed with the purpose of enhancing collaboration between industry and academia.In the course of fleshing out the details, this proposal was selected for the Subsidy for Advanced Technology Demonstration and Evaluation Facility Development (a project for construction of “Centers to Facilitate the Development of Technology”) by the Ministry of Aiming to deliver cutting-edge medical care from OsakaAn integrated research center for collaboration among industry, academia, and government
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