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Immunity and Regeneration Integration Unit

7F

0704

Elucidation of the involvement of chronic inflammation during the pathogenic processes of various ophthalmic diseases and the creation of treatments

In Japan, retinitis pigmentosa, diabetic retinopathy, and age-related macular degeneration, all of which affect the retina, account for more than 30% of the cause of visual impairment. While chronic inflammation deteriorates pathological condition in these retinal diseases, the molecular mechanisms regulating disease progression have not been fully elucidated. Our goal of the project is to develop novel therapies for resolving chronic inflammation. We attempt drug discovery approach under physiological conditions close to human organs using the animal model and organoid of specific eye diseases based on the research achievements of Ophthalmology at Osaka University.

Responsible Department

Department of Ocular Immunology
and Regenerative Medicine

Research Partner

Otsuka Pharmaceutical Co., Ltd.

Project Members

Principal Investigator

NISHIDA Kohji

Professor

Department of Ophthalmology

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Members

SAKIMOTO Susumu

Specially Appointed Associate Professor

Department of Ocular Immunology and Regenerative Medicine

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FUKUSHIMA Youko

Specially Appointed Associate Professor

Department of Ocular Immunology and Regenerative Medicine

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URASHIMA Hiroki

Joint Research Collaborator

Otsuka Pharmaceutical Co., Ltd.

TSUKAMOTO Teruhisa

Joint Research Collaborator

Otsuka Pharmaceutical Co., Ltd.

YAMASHITA Daisuke

Joint Research Collaborator

Otsuka Pharmaceutical Co., Ltd.

OHMOTO Koji

Joint Research Collaborator;

Otsuka Pharmaceutical Co., Ltd.

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