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This unit promotes novel-concept research projects for diseases associated with immune abnormalities, such as novel drug research to target key molecule(s) that play an important role common to the pathogenesis of general immune-mediated and inflammatory diseases.

A-4

Clinical research for regulatory factors in tumor immunology

WADA Hisashi

Specially Appointed Professor, Department of Clinical Research in Tumor Immunology

Shionogi & Co., Ltd.

A-5

The development of immunotherapy targeting immune suppressive molecules and cells

OHKURA Naganari

Specially Appointed Professor, Department of Frontier Research in Tumor Immunology

Shionogi & Co., Ltd.

B-1

Development of the new therapy for fibrosis and inflammation induced by cardiovascular diseases

MORISHITA Ryuichi

Endowed Chair Professor, Department of Clinical Gene Therapy

Novartis Pharma K.K.

B-7

Innovative advanced chemotherapy of gastrointestinal cancer

SATOH Taroh

Endowed Chair Professor, Department of Frontier Science for Cancer and Chemotherapy

YAKULT HONSHA CO., LTD.
Chugai Pharmaceutical Co., Ltd.
ONO PHARMACEUTICAL CO., LTD.

B-10

Pleiotropic non-skeletal effects of active vitamin D analogue

HAMANO Takayuki

Endowed Chair Associate Professor, Department of Comprehensive Kidney Disease Research

Chugai Pharmaceutical Co., Ltd.

D-4

Therapeutic Vaccine as a next biologics

NAKAGAMI Hironori

Endowed Chair Professor, Department of Health Developent and Medicine

AnGes, Inc.

This unit consists of the projects which aim to establish regenerative therapies using induced pluripotent stem (iPS) cells, to develop pharmaceutical regeneration by the activation of in vivo stem cells, and to develop an industrial and fundamental technology in order to accelerate the commercialization of regenerative therapies in multiple fields.

A-8

Research and development of allogeneic mesenchymal stromal cells for clinical application

MIYAGAWA Shigeru

Specially Appointed Professor, Department of Advanced Stem Cell Therapy

SAWA Yoshiki

Professor, Department of Cardiovascular Surgery

ROHTO Pharmaceutical Co., Ltd.

A-10

Research and development to increase the availability of treatments for heart disease through regenerative medicine

YASHIRO Kenta

Specially Appointed Associate Professor, Department of Cardiac Regeneration and Therapeutics

SAWA Yoshiki

Professor, Department of Cardiovascular Surgery

Terumo Corporation
Dai Nippon Printing Co., Ltd.

A-11

Developing new regenerative treatments for cardiovascular diseases, such as severe heart failure (dilated cardiomyopathy and fulminant myocarditis), where those treatments are most needed

KAWAGUCHI Naomasa

Specially Appointed Associate Professor, Department of Drug Discovery Cardiovascular Regeneration

SAWA Yoshiki

Professor, Department of Cardiovascular Surgery

ONO PHARMACEUTICAL CO., LTD.

B-3

Development of total knee arthroplasty with normal knee function

SUGAMOTO Kazuomi

Endowed Chair Professor, Department of Orthopedic Biomaterial Science

Teijin Nakashima Medical Co., Ltd.

B-11

Development of cell culture systems using a self-assembling peptide gel for novel medical devices, tissue regeneration and support for drug discovery

SAKAGUCHI Hirokazu

Endowed Chair Associate Professor, Department of Advanced Device Medicine

Menicon Co. Ltd.

B-12

Development of new technology for the manufacturing, standardization and application of stem cell-based products

HAYASHI Ryuhei

Endowed Chair Professor, Department of Stem Cells and Applied Medicine

NISHIDA Kohji

Professor, Department of Ophthalmology

ROHTO Pharmaceutical Co., Ltd.

C-2

Optimizing the use of gel composition and collaborative development of dedicated delivery systems for carrying out "endoscopic intervention combined with regenerative medicine" using self-assembled peptide hydrogels as a scaffold for restoring defective tissue

DOKI Yuichiro

Professor, Gastroenterological Surgery

FUSO Pharmaceutical Industries, Ltd.

C-7

Development of arthroscopic devices for regenerative medicine

YOSHIKAWA Hideki

Professor, Department of Orthopaedic Surgery

Smith & Nephew Endoscopy KK

D-1

Establishment of an allogeneic cell transplantation therapy for cartilage repair using the gMSC

YOSHIKAWA Hideki

Professor, Department of Orthopaedic Surgery

TWO CELLS Co., Ltd.

This unit comprises the projects which attempt to develop novel concept therapies through the integration of immunology and regeneration medicine.

A-2

Development of technology for immune regulation and quality control of transplants in cell therapy

TOYOFUKU Toshihiko

Specially Appointed Professor, Department of Immunology and Regenerative Medicine

Medinet Co., Ltd.

A-6

Elucidation of the involvement of chronic inflammation during the pathogenic processes of various ophthalmic diseases and the creation of treatments

NISHIDA Kohji

Professor, Department of Ophthalmology

Otsuka Pharmaceutical Co., Ltd.

A-7

Establishing cancer profiling to develop ground-breaking, innovative, personalized medicine and therapeutics

ISHII Hideshi

Specially Appointed Professor, Department of Medical Data Science

Taiho Pharmaceutical Co., Ltd.
Kinshukai
UNITECH Co., Ltd.
IDEA Consultants, Inc.

A-13

Creating a new form of integrative medicine that combines advanced medicine and traditional medicine in order to resolve issues in the form of an increase in the elderly who need care or who are bedridden and an increase in cancer patients in a super aging society

HAGIHARA Keisuke

Specially Appointed Professor, Department of Advanced Hybrid Medicine

TSUMURA & CO.

B-6

Development of novel medicine for inducing scarless and functional tissue regeneration by mobilizing bone marrow mesenchymal stem cells

TAMAI Katsuto

Endowed Chair Professor, Department of Stem Cell Therapy Science

Genomix Co., Ltd.

D-2

Drug discovery research and preclinical development of novel drug candidates which induce tissue regeneration

TAMAI Katsuto

Endowed Chair Professor, Department of Stem Cell Therapy Science

Genomix Co., Ltd.

This unit is composed of interdisciplinary integration projects with not limited to immunology or regenerative medicine. We believe further integration of technologies and research outcomes from different areas is necessary for the development of novel medical technologies and therapies. 

A-1

AI systems that integrate clinical and genomic information to provide a high-performance framework to support decision-making

NAKAYA Akihiro

Specially Appointed Professor, Department of Genome Informatics

NEC Corporation

A-3

Development of home medical device for repetitive transcranial magnetic stimulation for the treatment of post-stroke, intractable neuropathic pain

SAITOH Youichi

Specially Appointed Professor, Department of Neuromodulation and Neurosurgery (Teijin Pharma)

Teijin Pharma Limited

A-9

Developing new therapies using innovative administration devices

KANEDA Yasufumi

Professor, Department of Gene Therapy Science

YAMASHITA Kunihiko

Specially Appointed Associate Professor, Department of Impulse Science for Medicine

Daicel Corporation

A-12

Development of techniques to regenerate and assemble excitable tissues and techniques for functional analysis of those tissues

LEE Jong-Kook

Specially Appointed Associate Professor, Department of Advanced Cardiovascular Regenerative Medicine

SCREEN Holdings Co., Ltd.
PerkinElmer Co., Ltd.    etc.

B-2

Development of cloud computing for regenerative medicine in Ophthalmology

NISHIDA Kohji

Professor, Department of Ophthalmology

TOPCON CORPORATION

B-5

Research of the glaucoma etiology using induced glia cells from iPS cells

TSUJIKAWA Motokazu

Endowed Chair Professor, Department of Visual Regenerative Medicine

Senju Pharmaceutical Co., Ltd.

C-3

Development of implantable wireless devices for functional restoration by brain machine interfaces

KISHIMA Haruhiko

Professor, Department of Neurosurgery

NIHON KOHDEN CORPORATION

C-6

Research and development of the evaluation and training methods about dynamic balance

NAKATA Ken

Professor, Department of Medicine for Sports and Performing Arts

PROTEA JAPAN Co., Ltd.