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This unit promotes novel-concept research projects for diseases associated with immune abnormalities, such as novel drug research to target key molecule(s) that play an important role common to the pathogenesis of general immune-mediated and inflammatory diseases.

A-4

Clinical research for regulatory factors in tumor immunology

WADA Hisashi

Specially Appointed Professor, Department of Clinical Research in Tumor Immunology

Shionogi & Co., Ltd.

A-5

The development of immunotherapy targeting immune suppressive molecules and cells

OHKURA Naganari

Specially Appointed Professor, Department of Frontier Research in Tumor Immunology

Shionogi & Co., Ltd.

A-20

Development of innovative therapies for intractable immune disease and cancer by targeting neuro, immune and metabolic regulatory factors

KUMANOGOH Atsushi

Professor, Department of Respiratory Medicine and Clinical Immunology

NARAZAKI Masashi

Specially Appointed Professor, Department of Advanced Clinical and Translational Immunology

Chugai Pharmaceutical Co., Ltd.

A-22

Development of cGMP manufacturing process for novel lipid-based nano-medicine by taking advantage of the in-line manufacturing platform technology

MATSUZAKI Takashi

Specially Appointed Associate Professor, Department of DDS Pharmaceutical Development

Shionogi Pharma Co., Ltd.

A-28

Analysis of the functions of pathological or physiological periostin

TANIYAMA Yoshiaki

Specially Appointed Professor, Department of Advanced Molecular Therapy

Periotherapia Co.,Ltd.

A-30

Specially Appointed Associate Professor, Department of Medicine for Cutaneous Immunological Diseases

FUJIMOTO Manabu

Professor, Department of Dermatology

Maruho Co., Ltd.

B-1

Development of novel diagnostic and therapeutic approaches for treating aging-associated diseases

MORISHITA Ryuichi

Endowed Chair Professor, Department of Clinical Gene Therapy

FunPep Co., Ltd.

B-14

Therapeutic Vaccines as Next Generation Biologics

NAKAGAMI Hironori

Endowed Chair Professor, Department of Health Developent and Medicine

AnGes, Inc.
FunPep Co., Ltd.

This unit consists of the projects which aim to establish regenerative therapies using induced pluripotent stem (iPS) cells, to develop pharmaceutical regeneration by the activation of in vivo stem cells, and to develop an industrial and fundamental technology in order to accelerate the commercialization of regenerative therapies in multiple fields.

A-15

Research and development of Next Generation Endoscopic Intervention extra medical equipment based on industry-academia consortium

NAKAJIMA Kiyokazu

Specially Appointed Professor, Department of Next Generation Endoscopic Intervention

DOKI Yuichiro

Professor, Department of Gastroenterological Surgery

University-Industry Collaboration Consortium

A-18

Development of medical equipment and biomechanical evaluation methods of activity for physical therapy/prevention for treatment of sports injury and disorder

NAKATA Ken

Professor, Department of Medicine for Sports and Performing Arts

TSUJII Akira

Specially Appointed Associate Professor (Lecturer), Department of Sports Medical Biomechanics

Stryker Japan K.K.
Akiyama Medical Co.,Ltd.
ORPHE Inc.
Interstem Co., Ltd.
StemCell Institute
TEIJIN NAKASHIMA MEDICAL CO.,LTD.
SUNWISE CO.,LTD.

A-25

Development of novel musculoskeletal regenerative medicine using new cell biology and tissue engineering methods

NAKATA Ken

Professor, Department of Medicine for Sports and Performing Arts

EBINA Kosuke

Associate Professor, Department of Musculoskeletal Regenerative Medicine

Taisho Pharmaceutical Co., Ltd.

A-26

Development of new therapy for cardiovascular diseases

MIYAGAWA Shigeru

Professor, Department of Cardiovascular Surgery

Terumo Corporation

B-3

Development of computer-aided diagnosis programs and patient-matched instruments

OKA Kunihiro

Endowed Chair Associate Professor, Department of Orthopedic Biomaterial Science

TEIJIN NAKASHIMA MEDICAL CO.,LTD.

B-11

Development of innovative medical devices using bionanotechnology

NISHIDA Kohji

Professor, Department of Ophthalmology

Menicon Co. Ltd.

B-12

Development of new technology for the manufacturing, standardization and application of stem cell-based products

HAYASHI Ryuhei

Endowed Chair Professor, Department of Stem Cells and Applied Medicine

ROHTO Pharmaceutical Co., Ltd.

This unit comprises the projects which attempt to develop novel concept therapies through the integration of immunology and regeneration medicine.

A-2

Development of technology for regulation and quality control of immune cells in cancer therapy

KUMANOGOH Atsushi

Professor, Department of Respiratory Medicine and Clinical Immunology

Otsuka Pharmaceutical Co., Ltd.

A-6

Elucidation of the involvement of chronic inflammation during the pathogenic processes of various ophthalmic diseases and the creation of treatments

NISHIDA Kohji

Professor, Department of Ophthalmology

Otsuka Pharmaceutical Co., Ltd.

A-7

Establishing cancer profiling to develop innovative, personalized medicine and therapeutics

ISHII Hideshi

Specially Appointed Professor, Department of Medical Data Science

Hirotsu Bio Science Inc.
Kinshu-kai Medical Corporation
IDEA Consultants Inc.
Kyowa-kai Medical Corporation
Unitech Co. Ltd.

A-13

We aim to address the challenges of frailty, declining birthrate, and cancer through the application of hybrid medicine

HAGIHARA Keisuke

Specially Appointed Professor, Department of Advanced Hybrid Medicine

TSUMURA & CO.

A-19

Development of stem cell-based gene therapy adapted for the regeneration-inducing medicine

KIKUCHI Yasushi

Specially Appointed Associate Professor, Department of Stem Cell Gene Therapy Science

StemRIM Inc.

A-21

New drugs for refractory neurological diseases through translational research

YAMASHITA Toshihide

Professor, Department of Molecular Neuroscience

ITOKAZU Takahide

Specially Appointed Professor, Department of Neuro-Medical Science

Mitsubishi Tanabe Pharma Corporation

A-29

1. Understanding the pathogenesis of inflammatory skin diseases associated with dysbiosis
2. Analysis of the impact of maintaining skin homeostasis on overall health span

FUJIMOTO Manabu

Professor, Department of Dermatology

MATSUOKA Yuumi

Professor, Immunology Frontier Research Center (IFReC)

ROHTO Pharmaceutical Co., Ltd.

B-6

Development of novel medicine for inducing scarless and functional tissue regeneration by mobilizing bone marrow mesenchymal stem cells

SAGA Kotaro

Endowed Chair Associate Professor, Department of Stem Cell Therapy Science

TAMAI Katsuto

Guest Professor, Department of Stem Cell Therapy Science

StemRIM Inc.

This unit is composed of interdisciplinary integration projects with not limited to immunology or regenerative medicine. We believe further integration of technologies and research outcomes from different areas is necessary for the development of novel medical technologies and therapies. 

A-9

Developing new molecular therapies using Pyro-drive Jet Injector

KUMANOGOH Atsushi

Professor, Department of Respiratory Medicine and Clinical Immunology

YAMASHITA Kunihiko

Specially Appointed Associate Professor, Department of Device Application for Molecular Therapeutics

Daicel Corporation

A-16

Research and development of neural informatics, modulation and restoration

HIRATA Masayuki

Specially Appointed Professor, Department of Neurological Diagnosis and Restoration

KISHIMA Haruhiko

Professor, Department of Neurosurgery

NIHON KOHDEN CORPORATION
Ricoh Company, Ltd.
Murata Manufacturing Co., Ltd.
JiMED Inc.

A-17

Research and development of social implementation on health maintenance by integration of musculoskeletal regenerative medicine and sports/health epidemiology

NAKATA Ken

Professor, Department of Medicine for Sports and Performing Arts

TANAKA Hiroyuki

Specially Appointed Professor, Department of Sports Medical Science

Saraya Co., Ltd.

A-24

Building new clinical evidence by integrating clinical trial data and real world data (RWD)

HIDA Eisuke

Specially Appointed Professor

SHIONOGI & Co., Ltd.

A-27

Investigation of the effect of mouthwash on the reduction of salivary SARS-CoV-2 in patients with mild or asymptomatic COVID-19

KUTSUNA Satoshi

Professor, Department of Infection Control and Prevention

ONOZUKA Daisuke

Specially Appointed Associate Professor, Department of Oral Microbe Control

Earth Corporation

A-31

Innovation of cutting-edge fundamental technologies to accelerate drug discovery and regenerative medicine: Creation of physiologically-relevant cardiac tissues, and Development of system to acquire/evaluate biomedical information

SAKATA Yasushi

Professor, Department of Cardiovascular Medicine

CELLINK Bioprinting AB
SUZUKEN CO., LTD.
Alpha MED Scientific Inc.
AFI Corporation.

B-2

Regenerative medicine research and development of cloud computing for regenerative medicine in Ophthalmology

NISHIDA Kohji

Professor, Department of Ophthalmology

TOPCON CORPORATION

C-9

Research and development of precision diagnostics by highly sensitive spectroscopy
(Life and Medical Photonics Division, Institute for Open and Transdisciplinary Research Initiatives (OTRI))

KISHIMA Haruhiko

Professor, Department of Neurosurgery

FUJITA Katsumasa

Professor, Graduate School of Engineering

Sysmex Corporation