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This unit promotes novel-concept research projects for diseases associated with immune abnormalities, such as novel drug research to target key molecule(s) that play an important role common to the pathogenesis of general immune-mediated and inflammatory diseases.
A-4
Clinical research for regulatory factors in tumor immunology
WADA Hisashi
Specially Appointed Professor, Department of Clinical Research in Tumor Immunology
Shionogi & Co., Ltd.
A-5
The development of immunotherapy targeting immune suppressive molecules and cells
OHKURA Naganari
Specially Appointed Professor, Department of Frontier Research in Tumor Immunology
Shionogi & Co., Ltd.
A-20
Development of innovative therapies for intractable immune disease and cancer by targeting neuro, immune and metabolic regulatory factors
KUMANOGOH Atsushi
Professor, Department of Respiratory Medicine and Clinical Immunology
NARAZAKI Masashi
Specially Appointed Professor, Department of Advanced Clinical and Translational Immunology
Chugai Pharmaceutical Co., Ltd.
A-22
Development of cGMP manufacturing process for novel lipid-based nano-medicine by taking advantage of the in-line manufacturing platform technology
MATSUZAKI Takashi
Specially Appointed Associate Professor, Department of DDS Pharmaceutical Development
Shionogi Pharma Co., Ltd.
A-28
Analysis of the functions of pathological or physiological periostin
TANIYAMA Yoshiaki
Specially Appointed Professor, Department of Advanced Molecular Therapy
Periotherapia Co.,Ltd.
A-30
Elucidation of disease mechanisms and therapeutic targets in cutaneous immune-mediated disorders from the perspective of resident memory T cells
FUJIMOTO Manabu
Professor, Department of Dermatology
WATANABE Rei
Guest Professor, Department of Medicine for Cutaneous Immunological Diseases
Maruho Co., Ltd.
B-1
Development of novel diagnostic and therapeutic approaches for treating aging-associated diseases
MORISHITA Ryuichi
Endowed Chair Professor, Department of Clinical Gene Therapy
FunPep Co., Ltd.
B-14
Therapeutic Vaccines as Next Generation Biologics
HAYASHI Hiroki
Endowed Chair Associate Professor, Department of Health Development and Medicine
NAKAGAMI Hironori
Guest Professor, Department of Health Development and Medicine
Daicel Corporation
FunPep Co., Ltd.
B-15
Development of next-generation designer cell with improved adipose-derived stem cells (ADSCs)
SHIMAMURA Munehisa
Endowed Chair Professor, Department of Gene＆Stem Cell Regenerative Therapy
AS Medical Support Co., Ltd.
B-16
Next-generation digital biomarker for early diagnosis of dementia
MORISHITA Ryuichi
Endowed Chair Professor, Department of Clinical Gene Therapy
TAKEDA Shuko
Endowed Chair Associate Professor, Department of Clinical Gene Therapy
Ai-BrainScience Inc.
This unit consists of the projects which aim to establish regenerative therapies using induced pluripotent stem (iPS) cells, to develop pharmaceutical regeneration by the activation of in vivo stem cells, and to develop an industrial and fundamental technology in order to accelerate the commercialization of regenerative therapies in multiple fields.
A-18
Development of medical equipment, biomechanical evaluation methods and novel musculoskeletal regenerative medicine for diagnosis, prevention and treatment of sports injury and disorders
NAKATA Ken
Professor, Department of Medicine for Sports and Performing Arts
TSUJII Akira
Specially Appointed Associate Professor (Lecturer), Department of Sports Medical Biomechanics
Stryker Japan K.K., Akiyama Medical Co.,Ltd.,
ORPHE Inc., Interstem Co., Ltd.,
StemCell Institute,
TEIJIN NAKASHIMA MEDICAL CO.,LTD.,
SUNWISE CO.,LTD.,
ASAHI KASEI PHARMA Corp.
A-26
Development of new therapy for cardiovascular diseases
MIYAGAWA Shigeru
Professor, Department of Cardiovascular Surgery
Terumo Corporation
B-3
Development of computer-aided diagnosis programs and patient-matched instruments
OKA Kunihiro
Endowed Chair Associate Professor, Department of Orthopedic Biomaterial Science
TEIJIN NAKASHIMA MEDICAL CO.,LTD.
B-12
Development of new technology for the manufacturing, standardization and application of stem cell-based products
SAKIMOTO Susumu
Endowed Chair Associate Professor, Department of Stem Cells and Applied Medicine
ROHTO Pharmaceutical Co., Ltd.
A-34
Development of Innovative Medical Devices using Bionanotechnology and drug development for corneal regeneration medicine
NISHIDA Kohji
Professor, Department of Ophthalmology
Menicon Co. Ltd.
This unit comprises the projects which attempt to develop novel concept therapies through the integration of immunology and regeneration medicine.
A-2
Development of immunomodulation technology and quality control technology in cell therapy
KUMANOGOH Atsushi
Professor, Department of Respiratory Medicine and Clinical Immunology
Otsuka Pharmaceutical Co., Ltd.
A-6
Elucidation of the involvement of chronic inflammation during the pathogenic processes of various ophthalmic diseases and the creation of treatments
NISHIDA Kohji
Professor, Department of Ophthalmology
Otsuka Pharmaceutical Co., Ltd.
A-7
Establishing cancer profiling to develop innovative, personalized medicine and therapeutics
DOKI Yuichiro
Professor, Department of Gastroenterological Surgery
ISHII Hideshi
Guest Professor, Department of Medical Data Science
Hirotsu Bio Science Inc.
Kinshu-kai Medical Corporation
IDEA Consultants Inc.
Kyowa-kai Medical Corporation
Unitech Co. Ltd.
A-13
We aim to address the challenges of frailty, declining birthrate, and cancer through the application of hybrid medicine
EGASHIRA Ryuichiro
Specially Appointed Assistant Professor, Department of Advanced Hybrid Medicine
HAGIHARA Keisuke
Guest Professor, Department of Advanced Hybrid Medicine
TSUMURA & CO.
A-19
Development of stem cell-based gene therapy adapted for the regeneration-inducing medicine
KIKUCHI Yasushi
Specially Appointed Associate Professor, Department of Stem Cell Gene Therapy Science
StemRIM Inc.
A-21
New drugs for refractory neurological diseases through translational research
YAMASHITA Toshihide
Professor, Department of Molecular Neuroscience
ITOKAZU Takahide
Specially Appointed Professor, Department of Neuro-Medical Science
Mitsubishi Tanabe Pharma Corporation
A-29
1. Understanding the pathogenesis of inflammatory skin diseases associated with dysbiosis
2. Analysis of the impact of maintaining skin homeostasis on overall health span
FUJIMOTO Manabu
Professor, Department of Dermatology
MATSUOKA Yuumi
Professor, Immunology Frontier Research Center (IFReC)
ROHTO Pharmaceutical Co., Ltd.
B-6
Development of novel medicine for inducing scarless and functional tissue regeneration by mobilizing bone marrow mesenchymal stem cells
SAGA Kotaro
Endowed Chair Associate Professor, Department of Stem Cell Therapy Science
TAMAI Katsuto
Guest Professor, Department of Stem Cell Therapy Science
StemRIM Inc.
This unit is composed of interdisciplinary integration projects with not limited to immunology or regenerative medicine. We believe further integration of technologies and research outcomes from different areas is necessary for the development of novel medical technologies and therapies.
A-9
Research and development of advanced devices for next-generation medical care
KUMANOGOH Atsushi
Professor, Department of Respiratory Medicine and Clinical Immunology
YAMASHITA Kunihiko
Specially Appointed Associate Professor, Department of Device Application for Molecular Therapeutics
Daicel Corporation
A-16
Research and development of neural informatics, modulation and restoration
KISHIMA Haruhiko
Professor, Department of Neurosurgery
HIRATA Masayuki
Guest Professor, Department of Neurological Diagnosis and Restoration
NIHON KOHDEN CORPORATION
Ricoh Company, Ltd.
Murata Manufacturing Co., Ltd.
JiMED Inc.
A-17
Research and development of social implementation on health maintenance by integration of musculoskeletal regenerative medicine and sports/health epidemiology
NAKATA Ken
Professor, Department of Medicine for Sports and Performing Arts
TANAKA Hiroyuki
Specially Appointed Professor, Department of Sports Medical Science
Saraya Co., Ltd.
A-24
Building new clinical evidence by integrating clinical trial data and real world data (RWD)
HIDA Eisuke
Specially Appointed Professor
SHIONOGI & Co., Ltd.
A-31
Innovation of cutting-edge fundamental technologies to accelerate drug discovery and regenerative medicine: Creation of physiologically-relevant cardiac tissues, and Development of system to acquire/evaluate biomedical information
LEE Jong-Kook
Specially Appointed Professor, Department of Cardiovascular Regenerative Medicine and Drug Discovery
SUZUKEN CO., LTD.
Alpha MED Scientific Inc.
AFI Corporation.
C-9
Research and development of precision diagnostics by highly sensitive spectroscopy
(Life and Medical Photonics Division, Institute for Open and Transdisciplinary Research Initiatives (OTRI))
KISHIMA Haruhiko
Professor, Department of Neurosurgery
FUJITA Katsumasa
Professor, Graduate School of Engineering
Sysmex Corporation
A-32
Research Evaluation of Safety and Impact in Long COVID Intervention with Ensitrelvir for National Cohort Efficacy (RESILIENCE study)
KUTSUNA Satoshi
Professor, Department of Infection Control and Prevention
ONOZUKA Daisuke
Specially Appointed Associate Professor, Department of Post-infectious diseases Therapeutics
Shionogi & Co., Ltd.
A-33
Exploration of Innovative Diagnostic and Therapeutic Approaches for Ocular Diseases
1. Development of advanced diagnostic imaging software
2. Creation of diagnostic equipment and clinical indices that enhance decision-making in the diagnosis and treatment of both ophthalmic and systemic diseases
NISHIDA Kohji
Professor, Department of Ophthalmology
MARUYAMA Kazuichi
Specially Appointed Associate Professor, Department of Vision Informatics
TOPCON CORPORATION
