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This unit promotes novel-concept research projects for diseases associated with immune abnormalities, such as novel drug research to target key molecule(s) that play an important role common to the pathogenesis of general immune-mediated and inflammatory diseases.

A-4

Clinical research for regulatory factors in tumor immunology

WADA Hisashi

Specially Appointed Professor, Department of Clinical Research in Tumor Immunology

Shionogi & Co., Ltd.

A-5

The development of immunotherapy targeting immune suppressive molecules and cells

OHKURA Naganari

Specially Appointed Professor, Department of Frontier Research in Tumor Immunology

Shionogi & Co., Ltd.

A-20

Development of innovative therapies for intractable immune disease and cancer by targeting neuro, immune and metabolic regulatory factors.

KUMANOGOH Atsushi

Professor, Department of Respiratory Medicine and Clinical Immunology

NARAZAKI Masashi

Specially Appointed Professor, Department of Advanced Clinical and Translational Immunology

Chugai Pharmaceutical Co., Ltd.

B-1

Development of a novel therapeutic approach for treating aging-associated diseases

MORISHITA Ryuichi

Endowed Chair Professor, Department of Clinical Gene Therapy

FunPep Co., Ltd.

B-7

Innovative advanced chemotherapy of gastrointestinal cancer

SATOH Taroh

Endowed Chair Professor, Department of Frontier Science for Cancer and Chemotherapy

YAKULT HONSHA CO., LTD.
Chugai Pharmaceutical Co., Ltd.
ONO PHARMACEUTICAL CO., LTD.

D-4

Therapeutic Vaccine as a next biologics

NAKAGAMI Hironori

Endowed Chair Professor, Department of Health Developent and Medicine

RAKUGI Hiromi

Professor, Department of Geriatric and General Medicine

AnGes, Inc.

D-5

Developing therapies that target specific splicing variants

SANADA Fumihiro

Endowed Chair Associate Professor, Department of Clinical Gene Therapy

TANIYAMA Yoshiaki

Guest Professor, Department of Clinical Gene Therapy

Periotherapia CO.

This unit consists of the projects which aim to establish regenerative therapies using induced pluripotent stem (iPS) cells, to develop pharmaceutical regeneration by the activation of in vivo stem cells, and to develop an industrial and fundamental technology in order to accelerate the commercialization of regenerative therapies in multiple fields.

A-8

Research and development of allogeneic mesenchymal stromal cells for clinical application

HATA Hiroki

Specially Appointed Associate Professor, Department of Advanced Stem Cell Therapy

SAWA Yoshiki

Professor, Department of Cardiovascular Surgery

ROHTO Pharmaceutical Co., Ltd.

A-10

Research and development to increase the availability of treatments for critical limb ischemia through regenerative medicine

SHIBUYA Takashi

Specially Appointed Professor, Department of Vascular Regeneration and Podiatry

SAWA Yoshiki

Professor, Department of Cardiovascular Surgery

Terumo Corporation
Dai Nippon Printing Co., Ltd.
Sumitomo Dainippon Pharma Co., Ltd.

A-11

Developing new regenerative treatments for cardiovascular diseases, such as severe heart failure (dilated cardiomyopathy and fulminant myocarditis), where those treatments are most needed

SAWA Yoshiki

Professor, Department of Cardiovascular Surgery

ONO PHARMACEUTICAL CO., LTD.

A-15

Research and development of next Generation Endoscopic Intervention extra medical equipment based on industry-academia consortium

NAKAJIMA Kiyokazu

Specially Appointed Professor, Department of Next Generation Endoscopic Intervention

DOKI Yuichiro

Professor, Department of Gastroenterological Surgery

University-Industry Collaboration Consortium

A-18

Development of medical equipment and physical therapy/prevention for treatment of sports injury and disorder

NAKATA Keni

Professor, Department of Medicine for Sports and Performing Arts

MAE Tatsuo

Specially Apointed Professor, Department of Sports Medical Biomechanics

Smith & Nephew KK
Stryker Japan K.K.
PROTEA JAPAN Co., Ltd.

B-3

Development of total knee arthroplasty with normal knee function

SUGAMOTO Kazuomi

Endowed Chair Professor, Department of Orthopedic Biomaterial Science

Teijin Nakashima Medical Co., Ltd.

B-11

Development of innovative medical devices using bionanotechnology

SAKAGUCHI Hirokazu

Endowed Chair Associate Professor, Department of Advanced Device Medicine

Menicon Co. Ltd.

B-12

Development of new technology for the manufacturing, standardization and application of stem cell-based products

HAYASHI Ryuhei

Endowed Chair Professor, Department of Stem Cells and Applied Medicine

NISHIDA Kohji

Professor, Department of Ophthalmology

ROHTO Pharmaceutical Co., Ltd.

This unit comprises the projects which attempt to develop novel concept therapies through the integration of immunology and regeneration medicine.

A-2

Development of technology for regulation and quality control of immune cells in cancer therapy

TOYOFUKU Toshihiko

Specially Appointed Professor, Department of Immunology and Molecular Medicine

Otsuka Pharmaceutical Co., Ltd.

A-6

Elucidation of the involvement of chronic inflammation during the pathogenic processes of various ophthalmic diseases and the creation of treatments

NISHIDA Kohji

Professor, Department of Ophthalmology

Otsuka Pharmaceutical Co., Ltd.

A-7

Establishing cancer profiling to develop ground-breaking, innovative, personalized medicine and therapeutics

ISHII Hideshi

Specially Appointed Professor, Department of Medical Data Science

Taiho Pharmaceutical Co., Ltd.
Kinshukai
UNITECH Co., Ltd.
IDEA Consultants, Inc.

A-13

Creating a new form of integrative medicine that combines advanced medicine and traditional medicine in order to resolve issues in the form of an increase in the elderly who need care or who are bedridden and an increase in cancer patients in a super aging society

HAGIHARA Keisuke

Specially Appointed Professor, Department of Advanced Hybrid Medicine

TSUMURA & CO.

A-19

Development of stem cell-based gene therapy adapted for the regeneration-inducing medicine.

KANEDA Yasufumi

Professor, Department of Gene Therapy Science

StemRIM Inc.

A-21

New drugs for refractory neurological diseases through translational research

YAMASHITA Toshihide

Professor, Department of Molecular Neuroscience

Mitsubishi Tanabe Pharma Corporation

B-6

Development of novel medicine for inducing scarless and functional tissue regeneration by mobilizing bone marrow mesenchymal stem cells

TAMAI Katsuto

Endowed Chair Professor, Department of Stem Cell Therapy Science

StemRIM Inc.

This unit is composed of interdisciplinary integration projects with not limited to immunology or regenerative medicine. We believe further integration of technologies and research outcomes from different areas is necessary for the development of novel medical technologies and therapies. 

A-1

AI systems that integrate clinical and genomic information to provide a high-performance framework to support decision-making

NAKAYA Akihiro

Specially Appointed Professor, Department of Genome Informatics

NEC Corporation

A-3

Development of home medical device for repetitive transcranial magnetic stimulation for the treatment of post-stroke, intractable neuropathic pain

SAITOH Youichi

Specially Appointed Professor, Department of Neuromodulation and Neurosurgery

Teijin Pharma Limited

A-9

Developing new molecular therapies using Pyro-drive Jet Injector

KANEDA Yasufumi

Professor, Department of Gene Therapy Science

YAMASHITA Kunihiko

Specially Appointed Associate Professor, Department of Device Application for Molecular Therapeutics

Daicel Corporation

A-12

Innovation of biotechnologies to accelerate stem-cell based disease modeling/drug discovery and myocardial regeneration therapy
~ Engineering of Physiolgically-comparable cardiac tissues ~

LEE Jong-Kook

Specially Appointed Professor, Department of Cardiovascular Regenerative Medicine

SCREEN Holdings Co., Ltd.    etc.

A-14

Development and clinical implementation of advanced genomic medicine

MAEDA Daichi

Specially Appointed Professor, Department of Clinical Genomics

Takara Bio Inc.

A-16

Research and development of neural informatics, modulation and restoration

HIRATA Masayuki

Specially Appointed Professor, Department of Neurological Diagnosis and Restoration

KISHIMA Haruhiko

Professor, Department of Neurosurgery

NIHON KOHDEN CORPORATION
Ricoh Company, Ltd.
Murata Manufacturing Co., Ltd.

A-17

Research and development of social implementation on health maintenance by integration of musculoskeletal regenerative medicine and sports/health epidemiology

NAKATA Ken

Professor, Department of Medicine for Sports and Performing Arts

TANAKA Hiroyuki

Specially Appointed Professor, Department of Sports Medical Science

Saraya Co., Ltd.

B-2

Development of cloud computing for regenerative medicine in Ophthalmology

KAWASAKI Ryo

Endowed Chair Professor, Department of Vision Informatics (Topcon)

TOPCON CORPORATION

B-10

Regulation of homeostasis in chronic kidney disease and its effect on other organs

HAMANO Takayuki

Guest Professor, Department of Inter-Organ Communication Research in Kidney Disease

Bayer Yakuhin, Ltd
TORII PHARMACEUTICAL CO., LTD.
Japan Tobacco Inc.
Roche Diagnostics K.K.

C-8

The "Team Do Sports Lab" : Sports medicine research using the IoT and AI to study the locomotorium, the cardiovascular system, the brain, and nutrition

MAE Tatsuo

Specially Appointed Professor, Department of Sports Medical Biomechanics

NAKATA Ken

Professor, Department of Medicine for Sports and Performing Arts

DENTSU INC.