Development of innovative therapies for intractable immune disease and cancer by targeting neuro, immune and metabolic regulatory factors

Immunology research has brought many new discoveries and findings as a driving force in medicine and life sciences. The achievements have been applied to the development of biologics for rheumatoid arthritis and allergic diseases, as well as to cancer immunotherapy with anti-immune checkpoint antibodies, and have a great impact on clinical practice today. However, there are still many intractable immune diseases and cancers for which there is no cure, and clinical applications based on research progress and new findings are required.

With these backgrounds, the project promotes integrated analysis and verify human-derived samples using advanced immunological techniques based on the research achievements of immunology at Osaka University. From the results obtained, we aim to develop new therapeutic methods by cooperation with Chugai Pharmaceutical Co., Ltd. drug discovery technology.

Principal Investigator