Development of novel diagnostic and therapeutic approaches for treating aging-associated diseases

Chronic inflammation plays a critical role in the pathogenesis of many aging-related diseases, including vascular diseases, Alzheimer’s disease, and cancer. As life expectancy continues to increase, the proportion of individuals affected by these diseases is also rising. Therefore, there is an urgent need to develop new methods for early diagnosis and effective treatment, with the ultimate goal of extending healthy life expectancy.

We aim to elucidate, at the molecular level, the mechanisms and pathophysiology of persistent chronic inflammation in aging-related diseases. Based on these findings, we seek to establish innovative and highly original diagnostic and therapeutic approaches. In particular, our research focuses on dementia, ischemic cardio-cerebrovascular diseases, and cancer metastasis and recurrence. We are investigating disease mechanisms and exploring therapeutic targets from multiple perspectives, including inflammation, immune responses, vascular injury, and tissue repair.

Furthermore, we actively promote translational research to bridge basic research findings with clinical applications. Through these efforts, we aim to advance innovative medical technologies originating in Japan and contribute to global healthcare.